Paracetamol, Phenylephrine HCl, and Chlorpheniramine Maleate Syrup

Paracetamol, Phenylephrine HCl, and Chlorpheniramine Maleate Syrup is a combination of three active ingredients: Paracetamol, Phenylephrine Hydrochloride, and Chlorpheniramine Maleate. This suspension is used to treat the symptoms of the common cold, which is a seasonal viral infection caused by rhinovirus. It also helps in recovery and building immunity. 

Paracetamol Phenylephrine Hydrochloride Chlorpheniramine Maleate Uses

It are commonly combined in medications to treat symptoms associated with colds, flu, and allergies. Here’s a breakdown of their uses:

1. Paracetamol

Purpose: Pain reliever (analgesic) and fever reducer (antipyretic).
Common Uses: Reduces headaches, muscle pain, sore throat pain, and lowers fever.

2. Phenylephrine Hydrochloride

Purpose: Nasal decongestant

Common Uses: Relieves nasal congestion and sinus pressure caused by colds, flu, or allergies.

3. Chlorpheniramine Maleate

Purpose: Antihistamine

Common Uses: Relieves allergy symptoms like runny nose, sneezing, and watery/itchy eyes. It can also help with post-nasal drip.

Combination Uses

This combination is typically found in over-the-counter medications aimed at treating multiple cold or allergy symptoms, including:

• Nasal and sinus congestion
• Headaches
• Fever
• Allergic reactions or seasonal allergies
• Sneezing and runny nose

How do Paracetamol, Phenylephrine HCl, and Chlorpheniramine Maleate work?

Paracetamol, phenylephrine HCl, and chlorpheniramine maleate suspension consist of analgesic and antipyretic paracetamol. This provides relief from painful sensations in the body along with decreasing the temperature of the body during fever. Chlorpheniramine is an anti-allergic that works by blocking the action of certain chemical messengers that cause inflammation. Phenylephrine is a nasal decongestant and treats stuffy noses by increasing the blood flow in nasal passages. By working together this syrup provides relief from the primary symptoms of the common cold such as runny nose, sore throat, congestion, cough, sneezing, headache, etc. 

Drug Group Interactions

Here is the list of drug groups that may interact with Paracetamol, Phenylephrine HCl, and Chlorpheniramine Maleate:

• Antianxiety drug
• Cough suppressants 
• Anti-allergic drugs 
• Anticonvulsants 
• Anti-bacterial
• Bronchodilator 
• Antidepressants 
• Sleeping agent 
• Pain and fever medicines 
• Pain killers 
• Muscle relaxants

Drug to Drug Interactions Checker List

Many drugs can interact with Paracetamol, Phenylephrine HCl, and Chlorpheniramine Maleate. Here are some of the major drugs that can interact with each other.

• Doxepin
• Clomipramine
• Brexanolone
• Amitriptyline 
• Ergonovine
• Furazolidone
• Imipramine
• Ketoconazole
• Desipramine
• Dihydroergotamine
• Linezolid
• Methylergonovine
• Nortriptyline
• Potassium Chloride
• Potassium Citrate
• Sodium Oxybate
• Trimipramine
• Zonisamide
• Pexidartinib
• Selegiline
• Iobenguane I 131
• Methysergide Maleate
• Tranylcypromine
• Methylene Blue
• Lomitapide
• Cocaine Topical
• Amoxapine

Drug-Food Interaction

• Avoid Paracetamol, Phenylephrine Hydrochloride, and Chlorpheniramine Maleate with cocoa beans and tea leaves, as they contain chocolate and caffeine. These products may increase the risk of serious side effects.
• Avoid taking alcohol as it may increase the risk of liver damage.

Drug-Disease Interaction

Paracetamol, Phenylephrine Hydrochloride, and Chlorpheniramine Maleate should used with caution in some diseases such as:

• Asthma
• Blockage in the stomach or intestines
• Chronic obstructive pulmonary disease (COPD)
• High Blood Pressure
• Diabetes
• Cardiovascular Disease
• Glaucoma
• Chronic bronchitis
• Hyperthyroidism
• Pheochromocytoma (tumour in the adrenal glands)
• Kidney, Liver, or urinary problems

Side Effects of Paracetamol, Phenylephrine HCl, and Chlorpheniramine Maleate Syrup

The significant side effects of paracetamol, phenylephrine HCl, and chlorpheniramine maleate suspension are listed below.

• Headache
• Insomnia
• Tachycardia
• Restlessness
• Precautions

Discuss the following health conditions with your healthcare professional before taking this medication.

• Allergies
• Pregnancy
• Breastfeeding
• Kidney Stones
• Liver Problems

Please note that this is for educational purposes only. It is recommended that you consult a healthcare professional before use.

Frequently Asked Questions (FAQs)

Can a person drive while taking  Paracetamol, Phenylephrine HCl, and Chlorpheniramine Maleate Syrup?

No, a person should not drive while taking this syrup.

Can a person consume alcohol while taking Paracetamol, Phenylephrine HCl, and Chlorpheniramine Maleate Syrup?

No, a person should not consume alcohol while taking this medicine. 

How do I store this medicine?

The medicine should be kept in a closed container in a cool and dry place away from the sunlight.

Is this suspension safe for pregnant women?

Inform a healthcare professional before taking this suspension if you’re pregnant.

Is Paracetamol, Phenylephrine HCl, and Chlorpheniramine Maleate Syrup safe for children?

Yes, if prescribed by the doctor.